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Interesting facts on Familial Polyposis Coli
Meaning and Definition of Familial Polyposis Coli
Familial Adenomatous Polyposis is the most commonly found adenomatous polyposis syndrome. This particular disorder is characterized by presence of hundreds or thousands of polyps, resembling boils or lumps along the internal lining layer of the colon i.e. the large intestine. The polyps usually are seen throughout the entire length of the colon.If the familial adenomatous polyposis is actually left untreated, you find majority of patients developing colon cancer, by the time they are 35-40 years old. This disorder usually runs in families.
Cause for formation of polyps within your large intestine
Symptoms of FAP- Familial Adenomatous Polyposis
These are the following symptoms associated with FAP. They are
Diagnosis for an FAPColonoscopy
A long flexible tube fitted with light and camera is passed through your anal canal to visualize the inner aspect of the large intestine. The patient is given a mild sedative pill to make him/her feel absolutely relaxed. Colonoscopy helps your doctor see the extent and number of polyps within your intestine, it also allows to take biopsy of suspicious polyps to detect cancer and visualize and biopsy other abnormal areas.
Here a blood sample is tested for the genetic mutation in close family members of the patient like parents, brothers and sisters to detect the presence of APC gene mutation. If a mom or dad has been detected with APC gene mutation there is 50% chance of children being affected with this mutation. If they test positive for the mutation, they need to undergo a colonoscopy to look for adenomatous polyps.
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